clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (adp) to its platelet receptor and the subsequent adp-mediated activation of the glycoprotein gpiib/iiia complex, thereby inhibiting platelet aggregation. oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. the aim of this investigation was ...

during the last decade, the expansion of urbanization and industrial activities caused serious environmental problems such as soil pollution. novel technologies are required to remediate soil contamination with toxic contaminants, including heavy metals and organic pollutants. in recent years, there have been increasing attempts to improve soil remediation efficiency. electrokinetic (ek) is an ...

a novel quaternary ammonium-based cationic gemini surfactant (s6) having 1,6 di-bromo hexane as a spacer, have been used and its interaction with insulin in aqueous solution (ph, 7.40) was investigated by several methods including fluorescence spectroscopy, uv-vis spectroscopy, circular dichroism, dynamic light scattering, ζ-potential measurements, conductivity and transmission electron microsc...

biopolymers are environmental friendly sources as renewable and sustainable substituents for petroleum-based polymers. application of these polymers is common in variety of industries including papermaking. herbalexudate gums have been used in papermaking industry for decades, especially paper recycling. in this study, gum polysaccharide exudates from baridje plant  (ferula gummosa) extracted a...

Background: Telomeres are particular sequences of DNA located at the end of the eukaryotic chromosomes that are essential for genome integrity. Telomere length in spermatozoa differs among males, as well as spermatozoa. Also, decreased telomere length in spermatozoa of infertile men is associated with the reduction of fertility potential and embryo quality. Density gradient centrifugation (DGC)...

The two-fluid flow is produced by the combined effects of electroosmotic force in a conducting liquid and pressure gradient force in a non-conducting liquid. The Poisson-Boltzmann and Navier-Stokes equations are solved analytically; and the effects of governing parameters are examined. Poiseuille number increases with increasing the parameters involved. In the absence of pressure gradient, the ...

The zeta potential magnitude and the duration of its changes have been thought to be directly related to the surface reactivity, the governing of osteoconductivity and availability of valuable information in determining the anticipated in-vivo performance of implants. In this study the zeta potential of plasma sprayed hydroxyapatite (HA) was evaluated in various simulated physiological solution...